Update of package insert – New safety information on use of Zoloft (sertraline) in pregnancy

A Dear Healthcare Professional Letter has been issued by Pfizer PFE Pte Ltd to inform healthcare professionals that the package inserts of Zoloft (sertraline) have been updated to include new safety information pertaining to its use in pregnancy. The new safety information includes a statement that observational studies have provided evidence of an increased risk (< 2-fold) of post-partum haemorrhage following exposure to selective serotonin reuptake inhibitors (SSRIs), including sertraline, especially within the month prior to birth. Please refer to the letter for details.
Healthcare professional, Industry member, Therapeutic Products
Published:

Dear Healthcare Professional Letters

8 Jul 2021

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of the letters can be found on the MOH Alert System, which is accessible via the Health Professionals Portal (HPP). HPP is a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://www.hpp.moh.gov.sg/, and follow the procedures below to access the MOH Alert system.

Step 1: Scroll down to the bottom navigation panel of the HPP web page. Under the Healthcare Professionals section, expand the dropdown option for ‘Healthcare Professional Portal’ and select your profession. You will be redirected to the specific HPP web page to log in.

Step 2: Click on the Restricted Content icon on the left panel of the web page and log in via SingPass.

Step 3: Click on the MOH Alert icon under the ‘Applications’ section.

Step 4: Click on the Drug Alert tab to view the DHCPLs.