Caution against use of quinine in nocturnal leg cramps

Beacons Pharmaceuticals would like to inform healthcare professionals about labelling updates for Quinine Sulphate 300mg Tablets. Due to the potential risk of serious haematological reactions associated with the use of quinine sulphate, the product insert has been updated to include warnings and precautions against the off-label use of quinine in the treatment or prevention of nocturnal leg cramps as the potential risks outweigh the benefit of this treatment. Other labelling updates include additional warnings on the risk of quinine-induced thrombocytopenia, development of hypersensitivity and an updated list of possible adverse reactions associated with use of quinine sulphate.

 
 
Healthcare professional, Therapeutic Products
Published:

Dear Healthcare Professional Letters

12 Dec 2019

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of the letters can be found on the MOH Alert System, which is accessible via the Health Professionals Portal (HPP). HPP is a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://www.moh.gov.sg/hpp/, and follow the procedures below to access the MOH Alert system.

Step 1: On the top navigation ribbon of webpage, select 'For Healthcare Professionals' followed by 'Health Professionals Portal' and click on the choice of profession. User will be redirected to the specific HPP webpage for the selected profession.

Step 2: Click on the Restricted Content icon on the left panel of webpage and login via SingPass.

Step 3: Click on the MOH Alert icon under ‘Applications’ section

Step 4: Click on the Drug Alert tab to view the DHCPLs.